SampliQ

SampliQ OPT Polymer

SampliQ OPT Polymer cartridges are appropriate for a broad range of samples, including weak acids, neutrals, and weak bases. SampliQ OPT utilizes a novel polyamide chemistry that makes OPT cartridges compatible with water and most organic solvents, as well as acidic and basic solvents with a pH level of 0 to 14. This resin technology also exhibits retention for both polar and non-polar compounds, based on its combined hydrophilic and lipophilic characteristics.

The predominant retention mechanism in OPT cartridges is reversed phase, which simplifies method development and compatibility for both GC and LC separations.

SampliQ SCX Polymer

Agilent's mixed-mode SampliQ Strong Cation Exchange (SCX) polymeric resin is a sulfonic acid-modified divinyl benzene polymer with both ion exchange and reverse phase retention properties. As a result, the SampliQ SCX resin exhibits excellent retention for both basic and neutral compounds over a wide range of hydrophilicity (log P). The resin is also resistant to a wide variety of solvents, is stable in pH ranges from 0 to 14, and is water-wettable.

SampliQ SAX Polymer

The Agilent SampliQ Strong Anion Exchange (SAX) polymeric resin is a mixed-mode, tertiary amine-modified divinyl benzene polymer that displays both anion exchange and reversed phase behavior. As a result, the SampliQ SAX resin exhibits excellent retention for both acidic and neutral compounds over a wide range of hydrophilicity (log P). In addition, the SampliQ SAX resin is inert to a wide variety of solvents, is water-wettable, and is stable in pH ranges from 0 to 14.

SampliQ C18EC

SampliQ C18EC products are based on bonded, endcapped, reversed-phase octadecylsilane (ODS) silica gel particles. The non-polar sorbent is endcapped (EC), reducing polar secondary interactions associated with surface silanol groups. Non-polar analytes should be more strongly retained compared with non-endcapped SampliQ C18 products. SampliQ C18EC has a 25% carbon loading.

SampliQ C18 ODS

SampliQ C18 ODS products are based on bonded, reversed phase (octadecylsilane), irregular, silica gel (silica) particles. This non-polar, non-endcapped sorbent provides additional polar interactions associated with the surface silanol groups. It also enhances retention of basic compounds compared with the corresponding endcapped sorbent. It is recommended as a general purpose SPE phase for both polar and non-polar analytes. SampliQ C18 has a 24% carbon loading.

SampliQ C8 Octyl

SampliQ C8 Octyl products are based on bonded, reversed phase (octylsilane), irregular, silica gel (silica) particles. This non-polar, non-endcapped sorbent is recommended as a general purpose SPE phase for non-polar analytes. For basic analytes, octyl sorbents often can increase the extraction efficiency and enhance their purity.

SampliQ Silica

SampliQ Silica SPE products are based on unbonded, activated irregular silica gel (silica) particles. The primary interaction available is polar (e.g. hydrogen bonding). The silanol groups are ionizable, so it can be used as a weak cation exchanger at intermediate pH values.

SampliQ Amino (NH2)

SampliQ Amino (NH2) SPE products are based on irregular, silica gel (silica) particles. This dual purpose sorbent can act either as a polar phase or weak anion exchanger. When conditioned with a non-polar solvent, e.g., hexane, it can hydrogen bond with any molecule containing -OH, -NH, or -SH functional groups. In an aqueous environment with pH 7.8 or less, it can function as a weak anion exchanger.

SampliQ Silica SCX

SampliQ Si-SCX SPE products are based on irregular silica gel (silica) particles. These strong cation exchange sorbents are used to extract positively charged basic compounds. This benzene-sulphonic acid-based sorbent has significant non-polar secondary interactions, with nominal capacity 0.3 meq/g.

SampliQ Silica SAX

SampliQ Si-SAX SPE products are based on irregular, silica gel (silica) particles. This strong anion exchanger is used to extract compounds capable of carrying a negative charge from both aqueous and non-aqueous solutions. They are ideally suited to the extraction of weak acids at pHs above their pKa. The nominal capacity is 0.6 meq/g.

SampliQ Florisil PR

SampliQ Florisil PR is a selective synthetic magnesia-silica adsorbent, specially processed to give consistent results when used for column cleanup and separation of chlorinated pesticide residues prior to identification and measurement of the pesticide by gas, thin layer, or paper chromatography.

SampliQ Carbon

SampliQ Carbon (graphitized) sorbents exhibit high affinity for organic polar and non-polar compounds from both non-polar and polar matrices, when used in reversed phase conditions. Because carbon is non-porous, it allows for rapid processing, and the adsorption does not require analyte dispersion into solid phase pores.

SampliQ C8/Si-SCX Mixed Mode

The use of mixed-mode stationary phases is widely accepted for the extraction of basic drugs from biological fluids. The SampliQ Mixed-Mode Reversed-Phase SPE product consists of an alkyl phase (C8) and a strong cation exchange phase (Si-SCX) in an optimized ratio that provides a dual retention mechanism. The C8 functionality interacts with the hydrophobic portions of an analyte while the Si-SCX functionality interacts with the protonated amine portion. The strong analyte interactions allow the use of more rigorous washing conditions to eliminate co-extractables that might interfere with UV detection or cause ion suppression effects in LC-MS. The SampliQ Mixed-Mode phase is manufactured with trifunctional silanes allowing for maximum stability and low leachability. The phase is non-endcapped which gives some added interaction between residual silanols and polar analytes helping to provide added retention characteristics.

SampliQ Evidex

Effective sample preparation is an important step in building compelling evidence in drugs-of-abuse cases. The Evidex SPE cartridge – suitable for all necessary methods – supports the kind of reliable, accurate separation that you need:

• Cartridge designed for SAMHSA (Substance Abuse and Mental Health Services Administration) drug classes: Amphetamine/Methamphetamine, PCP (angel dust), Benzoylecgonine (cocaine), Codeine/Morphine, THC-COOH (marijuana)
• Accurate, reproducible results (<5% RSD)
• Forgiving of minor errors of volumes and concentrations of reagents
• Tested to ensure lot-to-lot reproducibility, high recovery, and clean extracts with low background
• Proprietary mixed phase bonding chemistry

• SampliQ Brochure

  Overview of the SampliQ SPE products

• Agilent Sample Preparation Catalogue

  Consumable items for sample preparation from Agilent